HYPERLIPIDEMIAS

This study tests a 24-week program called Black Impact to improve heart health and reduce stress in Black men. About 340 Black men with below-ideal heart health will either join the program right away or be placed on a waitlist. The program includes weekly exercise, health educat…

This study tests a program to help people with high blood pressure and high cholesterol lower their risk of heart disease. About 1,980 adults from Penn Medicine primary care will be assigned to either the program or usual care. The program uses tools and behavior change support t…

This study looks at whether a protein called PCSK9 is higher in people with nephrotic syndrome (a kidney condition causing protein leakage) and if it relates to kidney damage. Researchers will compare blood and kidney tissue samples from 75 participants—those with the condition a…

This study looks at how a new cholesterol-lowering tablet, HRS-1301, behaves in people with mild, moderate, or severe kidney problems compared to those with healthy kidneys. About 36 adults aged 18 to 65 will take a single dose, and researchers will measure drug levels and safety…

This study looks at whether screening for social needs (like housing or food) with a focus on antiracism can help reduce chronic diseases such as high blood pressure, diabetes, and asthma. About 68,000 adults and children in primary care will take part. The goal is to see if this…

This study follows 50 people who have had a stroke and at least one risk factor like high blood pressure or diabetes. Researchers use repeated MRI scans over 15 months to watch how small blood vessel damage in the brain gets worse. The goal is to learn more about how this damage …