Hormone receptor-positive breast cancer
Clinical trials for Hormone receptor-positive breast cancer explained in plain language.
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Experimental combo therapy for advanced breast cancer tested in small early trial
Disease control Stopped earlyThis early-phase study tested a new treatment for people with advanced breast cancer that had stopped responding to standard therapies. The treatment combined a patient's own engineered immune cells (CLBR001) with an antibody drug (ABBV-461). The study aimed to find the safest do…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CANCER
Phase 1 • Sponsor: Calibr, a division of Scripps Research • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Cancer drug combo shows promise but study halted early
Disease control Stopped earlyThis study tested a combination of two drugs—pembrolizumab (an immunotherapy) and mifepristone (a hormone blocker)—in people with advanced HER2-negative breast cancer. The goal was to see if the combination could shrink tumors. The study was stopped early after enrolling 24 parti…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CANCER
Phase 2 • Sponsor: University of Chicago • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC