High-risk pregnancy

This study tests whether adding certolizumab (Cimzia) to standard care (heparin and aspirin) can prevent fetal death or early delivery in pregnant women with antiphospholipid syndrome (APS) and lupus anticoagulant. About 55 women will receive the drug early in pregnancy and be co…

This study tests whether regularly warming the legs with a portable sauna blanket can improve blood vessel health and lower the risk of high blood pressure disorders in pregnant women with obesity. About 118 women will use the blanket at home for 16 weeks, starting early in pregn…

This study will test whether Emotional Freedom Technique (a type of tapping) and music therapy can reduce stress, anxiety, and depression in women with a high-risk pregnancy due to early rupture of membranes. About 177 women will be randomly assigned to receive these therapies or…

This study tests whether an 8-week program of motor imagery exercises (mentally rehearsing movements without physically doing them) can improve well-being in 38 high-risk pregnant women prescribed bed rest. The exercises are delivered via tele-rehabilitation. The goal is to see i…

This study tests whether hypnobreastfeeding education can reduce anxiety and improve breastfeeding in high-risk pregnant women. Researchers will compare 34 women who receive the training with 34 who do not, measuring anxiety, breastfeeding intentions, and how well they adapt to b…

This study looks at whether a pregnant woman's beliefs about her baby's health and her anxiety levels are linked to the results of a common fetal heart monitoring test (non-stress test) in high-risk pregnancies. Researchers will ask women at 32 weeks or later to fill out question…

This study looks at whether a mother's thyroid hormone levels and anxiety scores are linked to the results of fetal heart monitoring (non-stress test) in high-risk pregnancies. Researchers will follow pregnant women at 32 weeks or later, recording routine thyroid tests, anxiety q…

This study tests whether a simple fetal ECG monitor worn at home can effectively track the health of babies in high-risk pregnancies. Fifty pregnant women who need weekly fetal testing will use the device for 30-minute sessions, three times a week, starting at 32 weeks. The goal …

This study is testing a new, non-invasive monitor (fetal magnetocardiography) to detect hidden heart problems in high-risk pregnancies that might lead to fetal death. Researchers will study 30 pregnant women with conditions like congenital heart disease or twin pregnancy. The goa…

This study is creating a large collection of biological samples and health data from 1,000 pregnant and postpartum people, including those with high-risk pregnancies and healthy volunteers. The goal is to build a resource that researchers can use to study pregnancy complications …