HEPATOCELLULAR CARCINOMA (HCC)
Clinical trials for HEPATOCELLULAR CARCINOMA (HCC) explained in plain language.
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New combo therapy shows promise for tough liver cancer cases
Disease control CompletedThis study looked at over 2,600 people with advanced liver cancer that had invaded major blood vessels. Researchers compared standard immunotherapy plus anti-angiogenesis drugs with and without a procedure called TACE (which delivers chemo directly to the liver). The goal was to …
Matched conditions: HEPATOCELLULAR CARCINOMA (HCC)
Sponsor: Zhongda Hospital • Aim: Disease control
Last updated May 26, 2026 03:20 UTC
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New drug shows promise in battle against advanced liver cancer
Disease control CompletedThis study tested a new drug, tislelizumab, against the standard treatment sorafenib for adults with advanced liver cancer that cannot be removed by surgery. Over 680 participants were randomly assigned to receive one of the two treatments. The goal was to see which drug worked b…
Matched conditions: HEPATOCELLULAR CARCINOMA (HCC)
Phase: PHASE3 • Sponsor: BeiGene • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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New combo therapy shows promise for tough liver cancer cases
Disease control CompletedThis study tested whether adding a liver-directed chemotherapy infusion (HAIC) to standard drug therapy (immunotherapy plus anti-angiogenesis drugs) improves survival in people with advanced liver cancer that has spread into the main blood vessel of the liver. Over 1,600 particip…
Matched conditions: HEPATOCELLULAR CARCINOMA (HCC)
Sponsor: Zhongda Hospital • Aim: Disease control
Last updated May 18, 2026 12:11 UTC
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Immunotherapy combo shrinks liver tumors before ablation in early trial
Disease control CompletedThis study tested whether giving the immunotherapy drug pembrolizumab before and after local ablation (using heat or radiation to destroy tumors) could help shrink liver cancers in 30 patients with early-stage hepatocellular carcinoma. The goal was to see if this approach could m…
Matched conditions: HEPATOCELLULAR CARCINOMA (HCC)
Phase: PHASE2 • Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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AI joins the radiology team: 10,000-Patient trial tests smarter liver tumor detection
Diagnosis CompletedThis completed study tested whether an artificial intelligence (AI) system can help doctors accurately identify liver tumors from contrast-enhanced CT scans. Over 10,000 adults participated, and the AI's main goal was to correctly tell malignant from non-malignant lesions. The ap…
Matched conditions: HEPATOCELLULAR CARCINOMA (HCC)
Phase: NA • Sponsor: Shengjing Hospital • Aim: Diagnosis
Last updated May 26, 2026 03:17 UTC
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AI and PET/MRI join forces to decode tumor aggressiveness
Knowledge-focused CompletedThis study tested whether combining PET/MRI scans with machine learning can more accurately determine how aggressive solid tumors like prostate cancer are. Researchers scanned 50 adults with prostate, liver, kidney, or brain tumors and compared the AI results to standard tissue a…
Matched conditions: HEPATOCELLULAR CARCINOMA (HCC)
Sponsor: Ciprian Catana, MD, PhD • Aim: Knowledge-focused
Last updated May 26, 2026 03:20 UTC
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Smart model helps surgeons pick best candidates for liver cancer surgery
Knowledge-focused CompletedThis study looked at 151 liver cancer patients whose tumors had spread into the bile ducts. Researchers used a special computer model to figure out which patients would benefit most from surgery. The goal was to help doctors make better, personalized decisions to improve long-ter…
Matched conditions: HEPATOCELLULAR CARCINOMA (HCC)
Sponsor: First Affiliated Hospital, Sun Yat-Sen University • Aim: Knowledge-focused
Last updated May 26, 2026 03:20 UTC
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AI model spots best candidates for Post-Surgery liver cancer treatment
Knowledge-focused CompletedThis study looked at 1005 liver cancer patients who had surgery to remove their tumors. Researchers used machine learning to figure out which patients would get the most benefit from an additional treatment called transarterial chemoembolization (TACE) after surgery. The goal was…
Matched conditions: HEPATOCELLULAR CARCINOMA (HCC)
Sponsor: Anhui Provincial Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 03:17 UTC
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Liver cancer patients: do Pre-Transplant drugs improve outcomes?
Knowledge-focused CompletedThis study looked back at data from 484 liver cancer patients who had a liver transplant. Researchers wanted to see if taking certain cancer drugs (tyrosine kinase inhibitors) before the transplant helped patients live longer or kept the cancer from coming back. The goal was to f…
Matched conditions: HEPATOCELLULAR CARCINOMA (HCC)
Sponsor: Hu Liangshuo • Aim: Knowledge-focused
Last updated May 26, 2026 03:14 UTC
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AI analyzes 7,000 patients to guide liver cancer care
Knowledge-focused CompletedThis study used artificial intelligence to analyze data from 7,000 people with liver cancer. The goal was to create a tool that helps doctors predict how well a patient might do with different treatments, like surgery or other therapies. The tool is designed to support personaliz…
Matched conditions: HEPATOCELLULAR CARCINOMA (HCC)
Sponsor: Sun Yat-sen University • Aim: Knowledge-focused
Last updated May 26, 2026 03:08 UTC
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CT scans may predict best treatment for liver cancer patients
Knowledge-focused CompletedThis study looked at 324 liver cancer patients to see if CT scans could predict who would benefit from a combination of two treatments: a procedure that blocks the tumor's blood supply (TACE) and a targeted drug (TKI). The goal was to find out if certain scan features could help …
Matched conditions: HEPATOCELLULAR CARCINOMA (HCC)
Sponsor: First Affiliated Hospital, Sun Yat-Sen University • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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New combo shows promise for tough liver cancer cases
Knowledge-focused CompletedThis study looked back at medical records of 300 adults with high-risk liver cancer in China. They received a combination of two drugs (atezolizumab and bevacizumab) plus chemotherapy directly into the liver artery. The goal was to see how well this treatment worked and how safe …
Matched conditions: HEPATOCELLULAR CARCINOMA (HCC)
Phase: NA • Sponsor: Sun Yat-sen University • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC