Hemophilia A
Clinical trials for Hemophilia A explained in plain language.
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Gene therapy aims to help hemophilia a patients make their own clotting factor
Disease control Not yet recruitingThis early-stage trial tests a gene therapy for people with hemophilia A, a bleeding disorder. The treatment uses a modified virus to deliver a working gene into the patient's own stem cells, which are then infused back. The goal is to help the body produce clotting factor VIII, …
Matched conditions: HEMOPHILIA A
Phase 1 • Sponsor: Shenzhen Geno-Immune Medical Institute • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Real-World study to track Jivi's bleeding prevention in kids
Disease control Not yet recruitingThis observational study will follow 40 children aged 7 to 12 with hemophilia A who are already prescribed damoctocog alfa pegol (Jivi) to prevent bleeding. Researchers will collect data from routine care, including bleeding episodes and treatment patterns, over two years. The go…
Matched conditions: HEMOPHILIA A
Sponsor: Bayer • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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New study tracks safety of clotting drug for hemophilia patients in india
Disease control Not yet recruitingThis study looks at the safety and effectiveness of Octocog alfa, a lab-made clotting factor, when used to treat sudden bleeding episodes in adults with severe hemophilia A. About 33 people in India who have used factor VIII before will take part. Researchers will track side effe…
Matched conditions: HEMOPHILIA A
Sponsor: Bayer • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New study to see if emicizumab protects Kids' joints from hemophilia damage
Disease control Not yet recruitingThis study will follow 20 children with hemophilia A who are starting emicizumab treatment. Researchers will measure pain, joint health, balance, and mobility over time to see if the drug helps protect the musculoskeletal system. The goal is to understand whether emicizumab can r…
Matched conditions: HEMOPHILIA A
Sponsor: Hasan Kalyoncu University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Scientists to examine liver tissue after gene therapy for hemophilia
Knowledge-focused Not yet recruitingThis observational study will take small liver samples from 8 adults with hemophilia A or B who had gene therapy at least 6 months ago. Researchers want to see how the gene therapy affected liver cells, including how many cells still carry the therapy and whether there is any liv…
Matched conditions: HEMOPHILIA A
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Sep 19, 2026 00:00 UTC
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Can a newer clotting factor keep its effectiveness in hemophilia a?
Knowledge-focused Not yet recruitingThis study looks at hemophilia A patients who have used Coageight, a recombinant factor VIII treatment, to see how many develop inhibitors, which are antibodies that block the treatment's effect. Researchers will test blood samples from about 262 male patients aged 2 and older wh…
Matched conditions: HEMOPHILIA A
Sponsor: AryoGen Pharmed Co. • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC
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Do newer hemophilia drugs protect joints better? study aims to find out
Knowledge-focused Not yet recruitingThis observational study looks at children with moderate or severe hemophilia A who are on one of two preventive treatments: a longer-acting factor VIII therapy (efanesoctocog alfa) or a non-factor therapy (emicizumab). Researchers want to see if there are differences in how well…
Matched conditions: HEMOPHILIA A
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Hemophilia a bone health under the microscope: which treatment wins?
Knowledge-focused Not yet recruitingThis study will follow 50 men with severe hemophilia A for five years to compare bone density between those taking emicizumab and those taking efanesoctocog alfa. Researchers will also measure bone remodeling markers and joint health. The goal is to see if one treatment is linked…
Matched conditions: HEMOPHILIA A
Sponsor: Arkansas Children's Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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New study aims to unlock why some children with hemophilia reject treatment
Knowledge-focused Not yet recruitingThis observational study will follow 500 children with hemophilia A who use non-factor therapy to prevent bleeding. Researchers want to understand why some children develop antibodies against factor VIII while others do not. By studying blood and stool samples over time, they hop…
Matched conditions: HEMOPHILIA A
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC