Hemoglobinopathies
Clinical trials for Hemoglobinopathies explained in plain language.
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Can a One-Time gene infusion free patients from transfusions?
Cure Not yet recruitingThis trial tests a gene therapy called YOLT-204 in people aged 14 to 35 with sickle cell disease or transfusion-dependent thalassemia. The goal is to see if a single intravenous dose can safely boost fetal hemoglobin levels, potentially reducing or eliminating the need for blood …
Matched conditions: HEMOGLOBINOPATHIES
Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Cure
Last updated Aug 21, 2026 00:00 UTC
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Selective cell removal may tame stem cell Transplant's dangerous side effect
Disease control Not yet recruitingThis study tests whether removing a specific type of immune cell (naive T cells) from a donor's stem cell graft can prevent graft-versus-host disease (GVHD), a serious complication where donor cells attack the recipient's body. The trial enrolls people with non-malignant blood di…
Matched conditions: HEMOGLOBINOPATHIES
Phase 2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC