Hemodynamic changes

Researchers are studying healthy adults who live above 2600 meters to see how their lungs respond when they descend to sea level for a week and then return to their usual altitude. The trial measures pulmonary resistance, which is how hard the heart must work to pump blood throug…

Researchers are studying what happens when people who live permanently above 2600 meters, such as in Quito, Ecuador, spend a week at sea level. They will measure lung blood pressure and other heart and lung functions in healthy adults and in patients with pulmonary arterial hyper…

This trial asks whether a one-week stay at sea level can lower blood pressure in the lungs of people with pulmonary arterial hypertension who live permanently above 2600 meters. Researchers will compare heart and lung measurements taken at high altitude with those taken after sev…

This study will observe 220 adults who have had cardiac surgery to see how respiratory acidosis (too much acid in the blood from breathing problems) affects the right side of the heart. Researchers will measure heart function and track ICU stay, breathing tube time, and medicatio…

This study looks at whether a special breathing maneuver during heart surgery can improve heart and lung function in children with congenital heart disease. About 80 children will be randomly assigned to receive either the maneuver or standard care. The goal is to see if this app…

This study looks at how different patient positions and doses of the numbing drug bupivacaine affect spinal anesthesia for urogenital surgery. About 100 adults will be randomly placed in one of four groups: low or standard dose, combined with lying flat or head-down position. The…