Heart failure preserved ejection fraction
Clinical trials for Heart failure preserved ejection fraction explained in plain language.
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New heart failure drug shows promise in early trial
Disease control CompletedThis Phase 2 study tested the safety and effectiveness of tovinontrine, an experimental drug, compared to a placebo in 303 adults with chronic heart failure with preserved ejection fraction. The main goal was to see if tovinontrine could lower a key biomarker (NT-proBNP) in the b…
Matched conditions: HEART FAILURE PRESERVED EJECTION FRACTION
Phase 2 • Sponsor: Cardurion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Gout drug allopurinol may boost heart function in african americans with resistant hypertension
Symptom relief CompletedThis study tests whether allopurinol, a common gout medication, can improve heart function in African American veterans with resistant hypertension. Participants take allopurinol for 8 weeks, and researchers measure changes in heart function, exercise ability, and quality of life…
Matched conditions: HEART FAILURE PRESERVED EJECTION FRACTION
Phase 2 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Sep 06, 2026 00:00 UTC