HEALTHY ADULT SUBJECTS

This early-stage study tested the safety and how the body processes a new oral form of the drug edaravone. It involved 74 healthy adult male volunteers who took single and multiple doses. The main goals were to check for side effects and measure how much of the drug got into the …

This early-stage study tested a new oral medication called edaravone in healthy adult men. Researchers wanted to see how the body processes the drug and if it interacts safely with other common medications like rosuvastatin, sildenafil, or furosemide. The study also compared how …

This study aimed to understand how eating different types of meals affects how the body absorbs and processes an oral form of the drug edaravone. It involved 16 healthy Japanese adults who took the drug under various dietary conditions, including fasting. The main goal was to gat…

This early-stage study aimed to understand how the body absorbs a liquid drug called edaravone when it is swallowed normally compared to when it is delivered through a thin tube placed in the nose and down to the stomach. It involved 36 healthy Japanese adults to check for safety…

This study aimed to see if a drug called ADL-018 works the same way in the body when given with an easy-to-use autoinjector pen compared to a traditional syringe. Researchers tested this in 150 healthy adults by measuring the drug levels in their blood and checking for side effec…

This study aimed to see if a new oral liquid form of the drug edaravone gets into the bloodstream similarly to the existing intravenous (IV) form. It involved 42 healthy Japanese adults who received a single dose of each version. The main goal was to compare the levels of the dru…

This study aimed to see if an experimental drug called MCI-186 could cause dangerous changes in heart rhythm. It involved 27 healthy male volunteers who received the drug at different doses and a placebo. Researchers carefully monitored their heart activity to check for any safet…