HEALTHY ADULT SUBJECTS

This study tested a new tablet version of the drug edaravone (TTYP01) to see if it works the same as the current injection and oral suspension forms. Twenty-nine healthy adults took each form in a random order. The goal was to check safety and how the drug moves through the body,…

This early-stage study tested an oral version of edaravone in 74 healthy adult men. The goal was to see how the drug moves through the body and whether it is safe. Participants took single or multiple doses of the drug as a liquid or suspension.

This study looked at whether MCI-186, an experimental drug, changes the heart's electrical activity (QT interval) in 27 healthy adult men. Participants received different doses of the drug and a placebo to compare effects. The goal was to check for heart rhythm risks, not to trea…

This study looked at how an oral form of edaravone interacts with other common drugs in healthy adult males. It also compared how Japanese and Caucasian men absorb and process the medication. The goal was to gather safety and drug-level information, not to treat any disease. 84 h…

This study tested whether giving ADL-018 using an autoinjector works the same as using a pre-filled syringe in 150 healthy adults aged 18 to 65. The goal was to compare how the drug moves through the body and to check safety. No treatment was given for any disease, so this study …

This study looked at how the drug edaravone enters the bloodstream when given as a liquid by mouth or through a feeding tube. Thirty-six healthy Japanese adults took a single dose in a crossover design. The goal was to see if both methods work the same way and are safe.

This study looked at whether an oral liquid form of edaravone works the same as the IV form in the body. It involved 42 healthy Japanese adults aged 20 to 45. The goal was to measure how much of the drug gets into the blood and how fast, not to treat any disease.

This study looked at how a single dose of SIM0718 injection is processed by the body in 178 healthy adults aged 18-50 in China. The main goal was to measure drug levels and check for side effects. It is an early-phase trial to gather basic safety and drug behavior information.

This study looked at how eating different types of meals changes the way the body absorbs and processes an oral form of edaravone. Sixteen healthy Japanese adults took the drug under various meal conditions, including fasting. The goal was to gather information, not to treat any …