Head and neck squamous cell carcinoma (HNSCC) - recurrent/metastatic (R/M)
Clinical trials for Head and neck squamous cell carcinoma (HNSCC) - recurrent/metastatic (R/M) explained in plain language.
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Can a new drug boost chemotherapy for head and neck cancer?
Disease control Not yet recruitingThis trial tests whether adding an experimental drug called Enlituo to a standard chemotherapy combination helps people with advanced, recurrent, or metastatic head and neck squamous cell carcinoma. Participants receive either the standard combination (Anyouping plus platinum-bas…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA (HNSCC) - RECURRENT/METASTATIC (R/M)
Phase 2/3 • Sponsor: Taizhou Mabtech Pharmaceutical Co.,Ltd • Aim: Disease control
Last updated Aug 30, 2026 00:00 UTC
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Can a painkiller blocker boost cancer immunotherapy?
Disease control Not yet recruitingThis early-phase trial tests whether adding axelopran—a drug that blocks opioid effects on the immune system—can help pembrolizumab (an immunotherapy) work better in people with advanced head and neck cancer who take opioids for pain. About 18 participants will receive both drugs…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA (HNSCC) - RECURRENT/METASTATIC (R/M)
Phase 1/2 • Sponsor: Glycyx Therapeutics • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New scan could sharpen detection of head and neck cancers
Diagnosis Not yet recruitingThis study tests a new radioactive tracer called 64Cu-DOTA-ECL1i that aims to make PET scans more accurate for head and neck cancer. Researchers will enroll 90 adults with newly diagnosed or recurrent/metastatic head and neck squamous cell carcinoma. The goal is to see if this tr…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA (HNSCC) - RECURRENT/METASTATIC (R/M)
Phase 2 • Sponsor: Washington University School of Medicine • Aim: Diagnosis
Last updated Jun 27, 2026 14:01 UTC