Graft-versus-host disease(GVHD)
Clinical trials for Graft-versus-host disease(GVHD) explained in plain language.
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Can a lung protein tame severe graft-versus-host disease?
Disease control CompletedThis phase 3 trial investigates whether adding alpha-1 antitrypsin (AAT) to standard corticosteroid therapy improves outcomes for people with high-risk acute graft-versus-host disease (GVHD) after a stem cell transplant. Participants receive either AAT plus steroids or a placebo …
Matched conditions: GRAFT-VERSUS-HOST DISEASE(GVHD)
Phase 3 • Sponsor: CSL Behring • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Can a new pill tame GVHD after transplant?
Disease control CompletedThis large Phase 3 study tested whether adding the drug itacitinib to standard steroids helps control acute graft-versus-host disease (GVHD) in people who had a stem cell transplant for blood cancer. About 439 participants received either itacitinib or a placebo along with steroi…
Matched conditions: GRAFT-VERSUS-HOST DISEASE(GVHD)
Phase 3 • Sponsor: Incyte Corporation • Aim: Disease control
Last updated Jun 26, 2026 13:19 UTC