Genetics

This study looks at how genetic risk for type 2 diabetes affects the body's response to sugar. Researchers will give a sugary drink to 100 non-diabetic people aged 10-70 with high or low genetic risk scores. They will measure blood sugar, insulin, and body fat to see if those wit…

Researchers are building a long-term health study of 150,000 children born in Victoria, Australia, and their parents. The study follows participants from birth over their lifetime, collecting data on health, development, and environment through surveys, biosamples, and linked rec…

This study aims to understand why fatty plaques in heart arteries suddenly rupture, causing heart attacks, and why some people experience more heart muscle damage than others. Researchers will use advanced imaging, blood tests, and genetic analysis in about 2,000 patients undergo…

This study investigates why some people with moderate aortic valve stenosis get worse while others remain stable. Researchers will analyze immune system markers and detailed heart images from about 938 participants to find patterns that predict disease progression. The goal is to…

This study looks at how a person's genetics, gut microbiome, and behaviors influence how well they tolerate and respond to the weight-loss drug tirzepatide. Researchers will follow 200 overweight or obese adults for up to 12 months, tracking weight changes, side effects, and whet…

This study looks for new genetic causes of congenital sideroblastic anemias, a group of rare blood disorders where the body cannot properly use iron to make red blood cells. Researchers will analyze DNA from 20 people whose genetic cause is still unknown. The goal is to find and …