GENETIC PREDISPOSITION TO DISEASE

This study looked at whether telling overweight East Asians their genetic risk for type 2 diabetes, combined with using a Fitbit, could encourage them to be more active. 355 participants aged 40-60 were split into groups: some got just a Fitbit, others got their genetic risk plus…

This study looked at whether certain gene changes (in the TCF7L2 gene) make ICU patients with organ failure more likely to develop high blood sugar. Nearly 1,000 adults in the ICU were checked for these gene changes and their blood sugar levels. The goal was to understand the lin…

This study looked at how to return genetic test results to people in two large heart studies. Researchers checked if participants wanted their results, how much it cost, and if it changed their medical care. The goal was to learn the best way to share genetic information with hea…

This study looked at how women feel and think after getting a personalized estimate of their breast cancer risk. Researchers used a special computer model (BOADICEA) to give each woman a risk score based on her genes. The goal was to see if this personalized information changes h…

This study followed 43 infants with rare genetic disorders to track their development from birth up to age 3, with medical records reviewed until age 18. Researchers used a standard developmental assessment tool to understand each child's unique needs. The goal was to gather info…

This study looked at the best ways to encourage genetic testing for people at high risk for breast and ovarian cancer. Over 1,300 participants received either a direct message or a doctor alert to prompt testing. The goal was to see which method helped more people get tested and …

This study looked at whether whole genome sequencing can help screen healthy babies for genetic health risks. Researchers enrolled 500 infants and their parents from three U.S. cities, took a small blood sample from each baby, and sequenced the DNA of half the group. After three …