GENERALIZED MYASTHENIA GRAVIS (GMG)

This study tests a daily injection called zilucoplan in 15 adults hospitalized with severe generalized myasthenia gravis (gMG) that affects breathing or swallowing. The goal is to see if the drug quickly improves daily living activities over 2 weeks and continues to help for 12 w…

This early study tests an injection called GC012F in 6 people with refractory generalized myasthenia gravis, a condition causing severe muscle weakness. The main goal is to check safety and see if the treatment helps. Researchers will monitor side effects and measure how the ther…

This study is testing how safe and effective different drug combinations are for people with myasthenia gravis, a condition that causes muscle weakness. Researchers want to find treatments that reduce side effects and improve quality of life. About 70 adults with generalized MG a…

This study tests whether adding empasiprubart to the standard treatment efgartigimod can further improve symptoms in people with generalized myasthenia gravis (gMG) who still have muscle weakness. About 70 adults with a specific antibody type (AChR-Ab positive) will receive the c…

This study monitors 75 pregnant or postpartum women who have taken Ultomiris for conditions like PNH or aHUS. Researchers will track pregnancy outcomes and infant health up to one year after birth. The goal is to better understand any risks or complications linked to the drug dur…

This study follows 100 adults in Italy with generalized myasthenia gravis (gMG) who are already starting treatment with efgartigimod as part of their routine care. Researchers will track changes in symptoms and daily functioning over up to 23 months using patient surveys and doct…

This study looks at how doctors in Russia currently treat a rare muscle-weakening disease called generalized myasthenia gravis (gMG). Researchers will collect medical records and follow about 450 adults with the AChR-antibody form of the disease to see which treatments are used a…