GASTRO ESOPHAGEAL REFLUX

This study looks at whether stomach and esophagus movement problems increase the risk of aspiration (food or liquid going into the lungs) in children with neurologic impairment. About 120 children aged 5-21 who rely on feeding tubes and are at high risk for aspiration pneumonia w…

This study tests a procedure called ARAT that uses a special gas (argon plasma) during an endoscopy to treat chronic acid reflux. About 36 adults with frequent heartburn or regurgitation will be randomly assigned to get the real procedure or a sham (fake) procedure. The goal is t…

This study tests whether closing a small opening in the diaphragm (hiatal closure) can control early GERD. Researchers will enroll 40 adults aged 18-50 with mild reflux and a small hiatal defect. Participants will have surgery to close the defect, and the study will measure if th…

This study compares two weight-loss surgeries for people with severe obesity and acid reflux (GERD). About 560 participants will be randomly assigned to either a newer procedure (Nissen-Sleeve) or the standard Roux-en-Y gastric bypass. The main goal is to see if the newer surgery…

This study aims to find out how many children in the Czech Republic have symptomatic gastroesophageal reflux disease (GERD). Researchers will survey about 1,000 children aged 8-9 and 12-13 through schools. Those with symptoms like heartburn or regurgitation may undergo further te…

This study is testing a wearable device called C-mo System to see how well it can automatically detect and describe coughs in people with conditions like asthma, COPD, or chronic cough. About 300 participants aged 2 and older will wear the device for 24 hours and complete diaries…

This study will collect data from 90,000 adults to compare two methods of taking tissue samples from the esophagus: standard forceps biopsies and a brush-based method called WATS3D. The goal is to see which approach better detects Barrett's esophagus, dysplasia, and other esophag…