FUNGAL INFECTION

This early-stage study tested a new oral drug called APX001 in 46 healthy adults to see if it is safe and how the body processes it. The goal was to gather information for future development of a treatment for fungal infections. Participants received either the drug or a placebo,…

This study looked at whether using special tests (biomarkers) for fungal infections could help doctors safely stop antifungal medicines earlier in intensive care patients. The goal was to reduce the number of days patients receive these drugs, which can have side effects. The stu…

This study tested a new medicine called rezafungin to see if it can prevent serious fungal infections in adults getting a bone marrow transplant. About 600 participants received either rezafungin or the standard treatment. The goal was to see if rezafungin works better at keeping…

This study tested a gel called CGB-400 on 15 adults with toenail fungus. The goal was to see if the gel could clear the fungus and make nails look better. Participants applied the gel for up to 12 weeks, with follow-up visits to check progress.

This study tracked 219 adults with severe COVID-19 who needed a ventilator to breathe. Researchers wanted to see how many also developed serious fungal infections, especially from a mold called Aspergillus. They used standard tests to check for these infections, but did not give …

This early-stage study tested the safety and tolerability of a new antifungal drug called APX001 in about 80 healthy adults. Participants received either the drug or a placebo to check for side effects and how the drug moves through the body. The goal was to gather initial safety…