FGFR GENE ALTERATIONS
Clinical trials for FGFR GENE ALTERATIONS explained in plain language.
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New hope for Hard-to-Treat cancers: first human trial of TYRA-430 begins
Disease control Recruiting nowThis early-stage study tests a new oral drug, TYRA-430, in about 100 adults with advanced liver cancer or other solid tumors that have specific genetic changes (FGF/FGFR pathway). The main goals are to find a safe dose and check for side effects. Researchers will also look for si…
Matched conditions: FGFR GENE ALTERATIONS
Phase: PHASE1 • Sponsor: Tyra Biosciences, Inc • Aim: Disease control
Last updated May 26, 2026 11:32 UTC
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New pill targets rare cancer gene mutations in last-resort patients
Disease control Recruiting nowThis study tests an experimental drug called E7090 in 75 people with advanced or recurrent solid tumors that have a specific genetic change (FGFR alteration). Participants must have tried other treatments without success or have no standard options left. The main goal is to see i…
Matched conditions: FGFR GENE ALTERATIONS
Phase: PHASE2 • Sponsor: National Cancer Center, Japan • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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New pill targets bladder Cancer's genetic weakness
Disease control Recruiting nowThis study tests a new drug called TYRA-300 in people with a low-grade, intermediate-risk bladder cancer that has not invaded the muscle. The drug targets tumors with specific changes in the FGFR3 gene. About 90 adults will take the drug to see if it shrinks tumors and delays can…
Matched conditions: FGFR GENE ALTERATIONS
Phase: PHASE2 • Sponsor: Tyra Biosciences, Inc • Aim: Disease control
Last updated May 14, 2026 12:02 UTC