Extrahepatic cholangiocarcinoma
Clinical trials for Extrahepatic cholangiocarcinoma explained in plain language.
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Experimental antibody takes on tough bile duct cancers
Disease control CompletedThis phase 2 trial tests an experimental drug called XmAb20717 in 27 adults with advanced biliary tract cancers (bile duct or gallbladder cancer) that worsened after standard chemotherapy. The drug is a bispecific antibody designed to activate the immune system against cancer by …
Matched conditions: EXTRAHEPATIC CHOLANGIOCARCINOMA
Phase 2 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Sep 21, 2026 16:00 UTC
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Immunotherapy combo shows promise for tough bile duct cancer
Disease control CompletedThis study tested whether adding the immunotherapy drug pembrolizumab to standard chemotherapy (gemcitabine/cisplatin) helps people with advanced bile duct or gallbladder cancer live longer. Over 1,000 participants received either the combination or chemo plus a placebo. The goal…
Matched conditions: EXTRAHEPATIC CHOLANGIOCARCINOMA
Phase 3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New drug ZW25 shows promise for rare bile duct cancer
Disease control CompletedThis study tested a drug called ZW25 (zanidatamab) in 87 people with advanced or metastatic HER2-amplified biliary tract cancer that had worsened after standard chemotherapy. The goal was to see if the drug could shrink tumors and how long that effect lasted. The trial is now com…
Matched conditions: EXTRAHEPATIC CHOLANGIOCARCINOMA
Phase 2 • Sponsor: Jazz Pharmaceuticals • Aim: Disease control
Last updated Jun 26, 2026 17:24 UTC