ER/PR(+), HER2(-) breast cancer
Clinical trials for ER/PR(+), HER2(-) breast cancer explained in plain language.
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New pill targets rare cancer mutation in early trial
Disease control Recruiting nowThis study tests a new drug called rezatapopt (PC14586) in people with advanced solid tumors that have a specific TP53 Y220C mutation. The drug is designed to reactivate the p53 protein, which normally helps stop cancer growth. The trial will also test rezatapopt combined with th…
Matched conditions: ER/PR(+), HER2(-) BREAST CANCER
Phase 1/2 • Sponsor: PMV Pharmaceuticals, Inc • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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New breast cancer surgery could spare women from unnecessary lymph node removal
Disease control Recruiting nowThis study is for women with early-stage luminal breast cancer that has spread to 1 or 2 lymph nodes. Instead of removing many lymph nodes from the armpit, surgeons will remove only the marked suspicious node and the sentinel nodes. If fewer than 3 nodes are positive, full lymph …
Matched conditions: ER/PR(+), HER2(-) BREAST CANCER
Sponsor: European Institute of Oncology • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC