Early-onset Alzheimer disease
Clinical trials for Early-onset Alzheimer disease explained in plain language.
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New drug targets Alzheimer's proteins in Early-Onset patients
Disease control Recruiting nowThis early-stage trial tests a drug called ALN-APP (mivelsiran) in 60 adults with mild cognitive impairment or mild dementia due to early-onset Alzheimer's disease. The drug is given via a spinal injection to see if it safely lowers certain proteins linked to Alzheimer's in the b…
Matched conditions: EARLY-ONSET ALZHEIMER DISEASE
Phase 1 • Sponsor: Alnylam Pharmaceuticals • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
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Can two drugs together stop Alzheimer's plaques from coming back?
Disease control Recruiting nowThis trial tests two experimental drugs, donanemab and RG6289, in people who carry a specific genetic mutation that causes an inherited, early-onset form of Alzheimer's disease. The study first gives donanemab to clear amyloid plaques from the brain, then randomly assigns partici…
Matched conditions: EARLY-ONSET ALZHEIMER DISEASE
Phase 2/3 • Sponsor: Banner Health • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC