Dry eye syndrome (DES)
Clinical trials for Dry eye syndrome (DES) explained in plain language.
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Dry eye tests may reveal a new marker for hand osteoarthritis
Diagnosis CompletedResearchers are testing whether dry eye symptoms and signs can serve as a predictive marker in people with hand osteoarthritis. Participants complete the Ocular Surface Disease Index questionnaire and undergo tear tests, including Schirmer tests, tear break-up time, and optical c…
Matched conditions: DRY EYE SYNDROME (DES)
Sponsor: Medipol University • Aim: Diagnosis
Last updated Aug 29, 2026 00:00 UTC
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Can hyaluronic acid eye drops soothe dry, irritated eyes?
Symptom relief CompletedResearchers are testing two eye drops that contain hyaluronic acid and amino acids in people with dry eye syndrome. Adults with moderate to severe dry eye receive the 0.30% drop, while those with mild dry eye receive the 0.15% drop. The study measures changes in eye surface stain…
Matched conditions: DRY EYE SYNDROME (DES)
Sponsor: Fidia Farmaceutici s.p.a. • Aim: Symptom relief
Last updated Sep 20, 2026 00:00 UTC
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Fewer drops, same relief? trial tests Twice-Daily systane complete against standard Four-Times-Daily regimen
Symptom relief CompletedThis trial investigates whether using Systane Complete eye drops twice a day works as well as using Thealoz Duo eye drops four times a day for adults with mild to moderate dry eye disease. Over 30 days, participants will use one of the two regimens and report symptom changes thro…
Matched conditions: DRY EYE SYNDROME (DES)
Sponsor: Instituto Internacional de Medicina y Terapia (IIMET) • Aim: Symptom relief
Last updated Jul 26, 2026 00:00 UTC
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Filtering serum eye drops: does it remove key healing molecules?
Knowledge-focused CompletedThis study involved 10 adults with severe dry eye disease who did not respond to standard treatments. Researchers measured levels of growth factors and vitamins in autologous serum eye drops before and after filtration, to see if filtering reduces their concentration. The goal is…
Matched conditions: DRY EYE SYNDROME (DES)
Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Eye drop study reveals hidden link between bacteria and dry eye relief
Knowledge-focused CompletedThis completed study looked at how two types of eye drops—cyclosporine A and hyaluronic acid—change the community of bacteria living on the eye's surface in people with dry eye syndrome. Fifty adults were randomly assigned to receive either cyclosporine plus hyaluronic acid or hy…
Matched conditions: DRY EYE SYNDROME (DES)
Sponsor: Hallym University Kangnam Sacred Heart Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:13 UTC