Drug drug interaction

Researchers are running a Phase 1 study to see how clemizole interacts with other medicines in healthy adults aged 18 to 55. In three parts, participants receive clemizole with itraconazole or phenytoin to measure whether those drugs change clemizole levels in the blood. A third …

This study investigates whether a new injectable drug called Y-3 changes how the body processes rosuvastatin, a widely used cholesterol-lowering medication. Twenty healthy adults aged 18 to 50 will take rosuvastatin alone and then together with Y-3 to measure any drug-drug intera…

This completed Phase 1 trial in 24 healthy adults checked whether an experimental injection called Y-3 changes how the body handles three common drugs: repaglinide (for diabetes), warfarin (a blood thinner), and omeprazole (for heartburn). Participants took these drugs alone and …

This early-stage study looked at how two common drugs—itraconazole (a fungal treatment) and rifampin (an antibiotic)—change the way the body processes KBP-5074, a potential medicine for high blood pressure or kidney disease. Twenty-four healthy adults took a single dose of KBP-50…