DRAVET SYNDROME
Clinical trials for DRAVET SYNDROME explained in plain language.
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New hope for dravet syndrome: phase 3 trial targets seizure control
Disease control Recruiting nowThis study tests an experimental drug called LP352 to see if it can safely reduce seizures in children and adults with Dravet syndrome, a severe form of epilepsy. About 160 participants will receive either LP352 or a placebo, and researchers will track changes in seizure frequenc…
Matched conditions: DRAVET SYNDROME
Phase: PHASE3 • Sponsor: Longboard Pharmaceuticals • Aim: Disease control
Last updated May 26, 2026 08:32 UTC
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New hope for kids with severe epilepsy: experimental drug ION337 enters human trials
Disease control Recruiting nowThis study tests a new medicine called ION337 in 32 children aged 2 to 12 with Dravet syndrome, a severe form of epilepsy. The main goal is to see if the drug is safe and tolerable when given as a spinal injection. Researchers will also measure how the drug moves through the body…
Matched conditions: DRAVET SYNDROME
Phase: PHASE1, PHASE2 • Sponsor: Ionis Pharmaceuticals, Inc. • Aim: Disease control
Last updated May 26, 2026 08:30 UTC
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New drug hopes to tame rare seizure disorder in kids and adults
Disease control Recruiting nowThis study tests an experimental drug called EPX-100 (clemizole hydrochloride) as an add-on treatment for people with Dravet syndrome, a rare and severe form of epilepsy. About 150 children and adults aged 2 and older will receive either the drug or a placebo for 20 weeks. The ma…
Matched conditions: DRAVET SYNDROME
Phase: PHASE3 • Sponsor: Epygenix • Aim: Disease control
Last updated May 26, 2026 08:28 UTC
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Hope for dravet families: phase 3 trial of zorevunersen launches
Disease control Recruiting nowThis study tests an experimental drug called zorevunersen (STK-001) in 170 children aged 2 to 17 with Dravet syndrome, a severe form of epilepsy. The goal is to see if the drug can reduce seizure frequency and improve daily living skills compared to a sham procedure. Participants…
Matched conditions: DRAVET SYNDROME
Phase: PHASE3 • Sponsor: Stoke Therapeutics, Inc • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Gene therapy trial aims to tame severe seizures in young children
Disease control Recruiting nowThis study tests a gene therapy called ETX101 in infants and children with Dravet syndrome, a severe genetic epilepsy. The treatment uses a harmless virus to deliver a working copy of the SCN1A gene to brain cells, aiming to reduce seizures and improve development. The trial incl…
Matched conditions: DRAVET SYNDROME
Phase: PHASE1, PHASE2 • Sponsor: Encoded Therapeutics • Aim: Disease control
Last updated May 20, 2026 11:56 UTC
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CBD study tracks seizure control in Tough-to-Treat epilepsies
Symptom relief Recruiting nowThis study follows about 100 people with Lennox-Gastaut, Dravet, or tuberous sclerosis complex who are prescribed Epidyolex (a CBD liquid) alongside their usual seizure medicines. Researchers will track how long people stay on the treatment and how many seizure-free days they hav…
Matched conditions: DRAVET SYNDROME
Sponsor: Jazz Pharmaceuticals • Aim: Symptom relief
Last updated May 26, 2026 08:35 UTC
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New brain scans aim to uncover why dravet patients face higher sudden death risk
Knowledge-focused Recruiting nowThis study uses PET and MRI scans to look at serotonin pathways in the brainstem of adults with Dravet syndrome, a severe form of epilepsy. Researchers want to see if these pathways are different in Dravet patients compared to those with other drug-resistant epilepsy and healthy …
Matched conditions: DRAVET SYNDROME
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated May 26, 2026 08:31 UTC
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New study aims to unlock secrets of rare childhood epilepsies
Knowledge-focused Recruiting nowThis study follows 1,000 children with rare epileptic syndromes like West and Dravet syndrome over time. Researchers will track how different treatments affect seizure frequency and the child's thinking and behavior. The goal is to gather real-world data to help doctors and famil…
Matched conditions: DRAVET SYNDROME
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 26, 2026 08:19 UTC
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New study tracks how dravet syndrome changes over time in kids
Knowledge-focused Recruiting nowThis study follows 50 children and young adults (ages 6 months to 21 years) with Dravet syndrome caused by SCN1A gene mutations. Researchers will measure changes in thinking, movement, and daily skills over 4 years using standard tests. They will also look for blood markers that …
Matched conditions: DRAVET SYNDROME
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC