Down syndrome regression disorder (DSRD)

Clinical trials for Down syndrome regression disorder (DSRD) explained in plain language.

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Can an immune-targeting antibody reverse sudden losses in down syndrome?

Disease control Not yet recruiting

Down syndrome regression disorder (DSRD) causes a sudden loss of thinking, language, or daily skills in some people with Down syndrome. Researchers are testing ublituximab, an antibody that targets immune cells, in 20 adults aged 18 to 40 who have DSRD and did not respond well en…

Matched conditions: DOWN SYNDROME REGRESSION DISORDER (DSRD)

Phase 2 • Sponsor: Jonathan Santoro • Aim: Disease control

Last updated Sep 12, 2026 00:00 UTC

Down syndrome regression disorder (DSRD)

Get alerted when new Down syndrome regression disorder (DSRD) trials appear

Can an immune-targeting antibody reverse sudden losses in down syndrome?