DLBCL
Clinical trials for DLBCL explained in plain language.
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Can a targeted drug boost the power of stem cell transplants for tough lymphoma?
Disease control Not yet recruitingThis phase 2 trial is testing whether adding the targeted drug pirtobrutinib to a standard chemotherapy conditioning regimen (BEAM) before an autologous stem cell transplant can improve outcomes for people with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The stu…
Matched conditions: DLBCL
Phase 2 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Aug 21, 2026 00:00 UTC
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New hope for aggressive lymphoma: triple-drug combo enters human trials
Disease control Not yet recruitingThis study tests a new combination of drugs for adults with diffuse large B-cell lymphoma (DLBCL) that has come back or not responded to previous treatment. About 46 participants will receive an experimental drug (EZH2 inhibitor) along with two other drugs (glofitamab and chemoth…
Matched conditions: DLBCL
Phase 1/2 • Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Gut check: could your microbiome boost lymphoma therapy?
Knowledge-focused Not yet recruitingThis study looks at whether the bacteria living in your gut can influence how well a drug called glofitamab works against diffuse large B-cell lymphoma (DLBCL). Researchers will collect stool samples from 30 patients before and after treatment to track changes in gut microbiome a…
Matched conditions: DLBCL
Sponsor: Peking Union Medical College Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC