Digestive system disease
Clinical trials for Digestive system disease explained in plain language.
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New pill shows promise for tough stomach cancer in early trial
Disease control OngoingThis first-in-human study tests an experimental oral drug called IDRX-42 in 278 adults with advanced gastrointestinal stromal tumors (GIST) that have spread or cannot be removed by surgery. The main goals are to check safety, find the right dose, and see if the drug can shrink tu…
Matched conditions: DIGESTIVE SYSTEM DISEASE
Phase 1 • Sponsor: IDRX, Inc., a wholly owned subsidiary of GSK, LLC • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
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One bite of gluten: scientists track the immune alarm in celiac disease
Knowledge-focused By invitation onlyResearchers at Boston Children's Hospital are studying how the immune system reacts after a single oral dose of gluten powder. The study includes people with celiac disease and healthy controls, all of whom follow a gluten-free diet before the test. By measuring blood levels of i…
Matched conditions: DIGESTIVE SYSTEM DISEASE
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Sep 13, 2026 00:00 UTC
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Blood test could spot returning colon cancer months before scans
Knowledge-focused OngoingThis study tests whether a simple blood test that looks for tumor DNA can detect colorectal cancer coming back earlier than standard CT scans. About 359 people who had surgery for stage II or III colorectal cancer will be randomly assigned to either the blood test plus frequent P…
Matched conditions: DIGESTIVE SYSTEM DISEASE
Sponsor: Claus Lindbjerg Andersen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC