Diffuse midline glioma, H3 K27-altered
Clinical trials for Diffuse midline glioma, H3 K27-altered explained in plain language.
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Nasal spray could deliver brain tumor treatment directly to Kids' tumors
Disease control Recruiting nowThis early-phase trial tests a nasal spray called NEO100 (a purified natural compound) in 12 children with certain aggressive brain tumors. The goal is to see if it's safe, find the best dose, and check if the drug reaches the tumor. Participants will receive increasing doses, an…
Matched conditions: DIFFUSE MIDLINE GLIOMA, H3 K27-ALTERED
Phase 1 • Sponsor: Neonc Technologies, Inc. • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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New hope for kids with relapsed cancers: experimental drug CBL0137 enters trial
Disease control Recruiting nowThis study tests a new drug called CBL0137 in children and young adults (ages 1 to 21) whose solid tumors, brain tumors, or lymphoma have returned or stopped responding to treatment. The goal is to find the best dose, check side effects, and see if the drug can shrink tumors. The…
Matched conditions: DIFFUSE MIDLINE GLIOMA, H3 K27-ALTERED
Phase 1/2 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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Radioactive drug targets brain tumors in early trial
Disease control Recruiting nowThis early-phase study tests a radioactive drug called 177Lu-PSMA-617 combined with standard chemotherapy (temozolomide) for people with aggressive IDH wild type gliomas. The goal is to see if the combination is safe and to get a first look at whether it helps control tumor growt…
Matched conditions: DIFFUSE MIDLINE GLIOMA, H3 K27-ALTERED
Phase 1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New hope for deadly brain tumors: Drug-Radiation combo trial opens
Disease control Recruiting nowThis study tests whether adding the drug VRT106 to standard radiation therapy can help control a rare, fast-growing brain tumor called diffuse midline glioma (including DIPG) in adults. About 10 participants aged 18 to 75 will receive the combination treatment. The main goal is t…
Matched conditions: DIFFUSE MIDLINE GLIOMA, H3 K27-ALTERED
Phase 2 • Sponsor: Guangzhou Virotech Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC