Diagnosis

Researchers are testing whether MRI scans can accurately show whether bladder tumors have grown into the muscle wall, a key factor in choosing treatment. The trial enrolls 150 adults with bladder tumors who are scheduled for a transurethral resection (TURB), a surgical biopsy. Do…

This trial tests a fluorescent probe called TTP-ICG that targets Trop2, a protein often found on oral cancer cells. Researchers will soak tissue samples from people with oral tumors in the probe and use near-infrared imaging to see if it can distinguish cancer from benign growths…

This study tests whether computer analysis of 3D dental scans can accurately detect gum disease, gingivitis, and cavities, compared to traditional manual exams. About 30 adults with at least one gum recession will participate. If successful, this approach could make dental diagno…

This study tests a new bedside tool called Adjust-Unlikely to safely reduce unnecessary imaging for pulmonary embolism (a blood clot in the lungs) in emergency patients. Researchers will enroll 4,000 adults in Canada to see if the tool accurately identifies who does not need a sc…

This study is testing whether a small, portable ultrasound probe (echOpen) can help doctors diagnose patients faster. About 100 adults who need a quick diagnosis will be included. Researchers will compare how long it takes to get a diagnosis when doctors use the probe versus when…

This study compares two ways to use MRI images during prostate biopsy: software fusion (computer-assisted) and cognitive fusion (doctor's visual estimate). Over 1,300 men with suspicious prostate lesions will be randomly assigned to one method. The goal is to see which technique …

This study is testing whether an augmented reality (AR) system can help doctors guide needles during MRI scans. The AR system overlays digital information onto the real world, potentially making procedures like biopsies or injections more precise. Researchers will enroll 25 peopl…

This study tests whether an AI tool can help doctors make more accurate diagnoses in kidney medicine. About 100 doctors will review up to 10 online patient cases. Some doctors will see AI suggestions before giving their final diagnosis, while others will not. Researchers will com…

This study looks at how well pelvic organs move in women with endometriosis using dynamic MRI. Researchers want to see if measuring this movement can help diagnose the disease better and explain why some treatments don't work. About 52 women with suspected endometriosis will take…

This study tests whether a short educational video can encourage Hispanic current and former smokers to get screened for lung cancer. Researchers will enroll 2,000 people aged 50-80 who smoke or quit recently. Participants watch the video and answer surveys to identify barriers a…