CYTOMEGALOVIRUS INFECTIONS

This study tested a vaccine called Triplex in 94 adults who have both HIV and cytomegalovirus (CMV). The goal was to see if the vaccine is safe and helps the immune system fight CMV better. Participants received two shots of either the vaccine or a placebo, and researchers monito…

This study tested a new vaccine against cytomegalovirus (CMV) in 339 healthy adults aged 18 to 50. The vaccine uses lab-made proteins to train the immune system to fight CMV. The main goal was to check safety and how well the body responds to the vaccine, with different dose leve…

This early-stage trial tested a new vaccine called SPYVLP01 designed to prevent cytomegalovirus (CMV) infection. Researchers gave the vaccine to 120 healthy adults aged 18-50 to see if it is safe and triggers an immune response. The study compared two different doses, with and wi…

This study tested whether giving special immune cells (T cells) that target CMV or adenovirus can help control these infections in people who had a stem cell transplant. Sixteen children and adults with signs of infection received the cells. The main goal was to see if the treatm…

This study tested whether giving early treatment for cytomegalovirus (CMV) and tuberculosis (TB) can help HIV-infected infants with severe pneumonia survive. Over 500 babies under one year old were enrolled. The goal was to see if this approach reduces deaths in the short and lon…

This study looked at a new blood test that detects a tiny piece of the CMV virus (called microRNA) to see if it can spot reactivation of the virus after a stem cell transplant. Researchers tested stored blood samples from 60 adult transplant patients and compared the new test's a…

This study followed 400 stem cell transplant recipients to see how well anti-CMV medications work in everyday hospital care. Researchers tracked infections, drug resistance, and side effects. The goal was to improve treatment guidelines for these high-risk patients.