CYTOMEGALOVIRUS INFECTIONS

This study tested a vaccine designed to strengthen the immune system's response to cytomegalovirus (CMV) in adults who have both HIV and CMV. 90 participants, all with well-controlled HIV on stable medication, received either two doses of the experimental vaccine or a placebo. Th…

This study was the first time a new vaccine candidate for cytomegalovirus (CMV) was tested in people. Researchers gave the vaccine, called SPYVLP01, to 120 healthy adults to check if it was safe and if it triggered an immune response. The main goal was to monitor for side effects…

This study tested a new vaccine designed to prevent cytomegalovirus (CMV) infections in healthy adults aged 18-50. Researchers gave 339 participants different dose levels of the vaccine to check for safety and see if it triggered an immune response. The main goal was to monitor s…

This study tested whether adding treatments for tuberculosis (TB) and cytomegalovirus (CMV) to standard pneumonia care improves survival in HIV-infected infants with severe pneumonia. Researchers in six African countries enrolled 563 hospitalized babies aged 1-12 months. Infants …

This study tested a new cell therapy for patients who develop dangerous viral infections after a stem cell transplant and don't respond to standard antiviral drugs. Doctors collected special immune cells (T cells) from the patient's original stem cell donor, grew cells that could…

This study tested a new blood test designed to detect cytomegalovirus (CMV) infection in people who have received a stem cell transplant. Researchers looked back at stored blood samples from 60 transplant patients to see if the new test, which looks for a specific viral marker, w…

This study observed 400 adult patients who received a stem cell transplant to see how well different anti-CMV drugs worked in real-world hospital settings. The goal was to track how often the drugs prevented or treated CMV infections, if the virus became resistant to the medicati…