Craving

This pilot trial tests whether a personalized brain stimulation technique can help people with methamphetamine use disorder. The approach uses closed-loop theta-burst stimulation, which delivers magnetic pulses to a specific brain region in real time, triggered by the person's ow…

This study tests whether cannabidiol (CBD), a compound from cannabis, can reduce alcohol withdrawal symptoms and cravings in people with moderate-to-severe alcohol use disorder. 105 adults will stay in a hospital for 5 days, receive either CBD or a placebo alongside standard care…

Researchers at the National Institute of Mental Health are studying how everyday feelings, like stress or frustration, influence decision-making. They will follow 420 adults aged 18 to 55, including healthy volunteers and people with varying levels of depression, anxiety, or addi…

This study aims to understand how inflammation in the body influences mood and alcohol cravings in people with alcohol use disorder (AUD). Researchers will give 64 participants (32 with AUD and 32 without) a single low dose of a substance that causes temporary inflammation or a p…

This clinical trial is testing a medical device that has not yet been approved by the U.S. FDA. Because the trial details are withheld, the exact purpose, participants, and approach are not publicly known. The study is likely gathering early information on the device's safety and…