Coronary heart disease

This trial tests whether taking a daily low dose of colchicine, an anti-inflammatory drug, can reduce the risk of heart attacks, strokes, and other heart problems in Chinese patients who have had a stent placed for coronary heart disease. Researchers will compare two different do…

This study tests whether inclisiran, a newer cholesterol-lowering drug, works better than standard treatments for Chinese patients with coronary heart disease. About 1,590 adults whose cholesterol is still high despite statins will receive either inclisiran or usual care. The mai…

This study looks at 1500 people with diabetes who had a heart procedure to open blocked arteries. Researchers are comparing two treatments: a drug-coated balloon and a drug-eluting stent. The goal is to see which one works better over the long term for this specific group of pati…

This trial tests whether a program called PAL2, delivered by community health workers, can help Black adults aged 40 to 75 lower their risk of heart disease. Participants live in the Cleveland area and have at least two risk factors, such as high blood pressure, high cholesterol,…

This study tests whether a 12-session physiotherapy program can improve frailty in people aged 70 and older with stable coronary heart disease. Participants will do guided exercises and mobility techniques led by physiotherapists. Researchers will also check medications, diet, an…

This study aimed to see if making physical activity into a game could help older hospital patients move more. Participants would have received daily text messages, set step goals, earned points, and worn a Fitbit to track their steps. The study was withdrawn before any patients w…

This study follows 2,600 adults with coronary heart disease and depression who received a stent. Researchers track major heart problems like heart attacks or death over one year to find what predicts these events. The goal is to better understand the link between depression and h…

This study is building a large biobank of health information and blood samples from 48,000 people with diabetes in Hong Kong. Researchers will analyze genetic and other markers to find better ways to predict serious complications like kidney failure, heart disease, and stroke. Th…

This study looks at two genetic markers (Cofilin-2 and Lactoferrin) in 84 adults with gum disease, some of whom also have coronary heart disease. Researchers measure changes in these markers and gum health after a standard deep-cleaning dental treatment. The goal is to better und…