CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY SYNDROME
Clinical trials for CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY SYNDROME explained in plain language.
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Early trial aims to train immune system to fight childhood cancers
Disease control TerminatedThis early-phase study aimed to test the safety and find the right dose of a two-drug immunotherapy (nivolumab and ipilimumab) for children, teens, and young adults whose cancers had returned or stopped responding to standard treatments. The drugs work by helping the patient's ow…
Matched conditions: CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY SYNDROME
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 02, 2026 14:56 UTC
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New hope for kids with aggressive brain cancers: early trial tests immune therapy
Disease control OngoingThis early-stage trial is testing the safety and early effectiveness of a drug called pembrolizumab in children with aggressive brain tumors that have come back or stopped responding to standard treatments. The drug is an immunotherapy, which aims to help the body's own immune sy…
Matched conditions: CONSTITUTIONAL MISMATCH REPAIR DEFICIENCY SYNDROME
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC