CONGENITAL HEART DISEASE (CHD)

This study tests a drug called sotatercept in 40 adults with a serious heart defect and Eisenmenger syndrome, a condition where blood flow in the lungs is blocked. The goal is to see if the drug can lower lung pressure and improve blood flow over 24 weeks. Participants will recei…

This study tests a smartphone app that listens to heart sounds to detect congenital heart disease. About 220 people aged 6 and older will have their heart sounds recorded during a regular hospital visit. The app's accuracy will be compared to standard tests to see if it can tell …

This study tests a virtual psychological program called HeartGPS for mothers whose unborn babies have congenital heart disease. About 210 mothers will either receive usual care or usual care plus HeartGPS starting during pregnancy. The goal is to see if the program lowers anxiety…

This study tests whether playing music or using a musical mobile can reduce pain and stress in infants when their chest tube is removed after heart surgery. About 54 babies aged 2 to 12 months will be randomly assigned to hear music, watch a musical mobile, or receive standard ca…

This study tests a digital exercise program that adjusts in real time to help children aged 6-12 recover after congenital heart disease surgery. Kids wear non-invasive monitors and follow daily exercises guided by a smartphone system. Researchers will compare their recovery with …

This study tests whether a butyric acid supplement is safe and can improve gut health in infants and young children (1 month to 3 years) with congenital heart disease who need heart surgery. Researchers will monitor side effects and check for changes in gut bacteria and inflammat…

This study will check 138 children with congenital heart disease for chromosomal abnormalities using a blood test. Researchers want to find out how common these genetic changes are and how they relate to specific heart problems. The goal is to improve early diagnosis and help fam…

This study looks at how congenital heart disease (CHD) affects growth in infants and toddlers aged 1 month to 2 years. Researchers will review medical records of 72 children to compare their weight, height, and head circumference against healthy growth standards. The goal is to b…

This study looks at ways to help mothers directly breastfeed their babies who have congenital heart disease (CHD). Researchers want to see if special support can increase breastfeeding rates and improve health for both the baby and the parent. About 266 mothers and their infants …

This study is testing a smartphone app called MedlyPeds that lets kids with heart disease send daily health updates to their doctors from home. About 30 children aged 8-18 with various heart conditions will use the app for 3 months. The goal is to see if the app is easy to use an…