Congenital abnormalities
Clinical trials for Congenital abnormalities explained in plain language.
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New heart valve passes safety check in 57 patients
Disease control CompletedThis study looked at the SAPIEN XT heart valve, which is placed through a thin tube (catheter) to fix a failed valve in the heart's right ventricle. Researchers wanted to confirm it is safe and works well. They enrolled 57 people with a narrowed or leaky heart valve conduit. The …
Matched conditions: CONGENITAL ABNORMALITIES
Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Does dolutegravir raise the risk of birth defects? eswatini study investigates
Knowledge-focused CompletedResearchers are tracking birth outcomes for infants born in Eswatini to mothers who took dolutegravir or other HIV drugs around the time of conception. The study compares rates of neural tube defects and other birth defects among babies born to HIV-positive women on dolutegravir,…
Matched conditions: CONGENITAL ABNORMALITIES
Sponsor: Elizabeth Glaser Pediatric AIDS Foundation • Aim: Knowledge-focused
Last updated Sep 12, 2026 00:00 UTC
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3D nerve mapping could make Kids' head and neck surgery safer
Knowledge-focused CompletedThis completed study tested a new 3D MRI technique to map cranial nerves in 7 children aged 1 to 5 with head and neck tumors or birth defects. The goal was to create detailed models that help surgeons avoid damaging important nerves during operations. The research focused on deve…
Matched conditions: CONGENITAL ABNORMALITIES
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC