CLL
Clinical trials for CLL explained in plain language.
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New combo aims to outshine standard therapy for blood cancer
Disease control OngoingThis phase 3 study tests whether a new drug pair (sonrotoclax plus zanubrutinib) works better than the current standard (venetoclax plus obinutuzumab) for people with untreated chronic lymphocytic leukemia (CLL). About 652 adults with CLL who need treatment will be randomly assig…
Matched conditions: CLL
Phase: PHASE3 • Sponsor: BeOne Medicines • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New dosing strategy aims to reduce tumor lysis risk in CLL patients
Disease control OngoingThis study tests different ways to start and increase the dose of sonrotoclax in adults with chronic lymphocytic leukemia (CLL). The main goal is to see if these new dosing schedules lower the risk of tumor lysis syndrome, a serious side effect. About 56 participants will be enro…
Matched conditions: CLL
Phase: PHASE1, PHASE2 • Sponsor: BeiGene • Aim: Disease control
Last updated May 18, 2026 12:03 UTC