Clinical stage I HPV-mediated (P16-positive) oropharyngeal carcinoma ajcc V8
Clinical trials for Clinical stage I HPV-mediated (P16-positive) oropharyngeal carcinoma ajcc V8 explained in plain language.
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A gentler path after surgery for HPV throat cancer?
Disease control OngoingThis phase 2 trial is testing whether people with HPV-related throat cancer can safely receive lower doses of radiation and chemotherapy after surgery, compared with the standard full-intensity approach. The goal is to see if this lighter treatment helps preserve swallowing funct…
Matched conditions: CLINICAL STAGE I HPV-MEDIATED (P16-POSITIVE) OROPHARYNGEAL CARCINOMA AJCC V8
Phase 2 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Could less radiation be enough for HPV throat cancer?
Disease control OngoingThis study compares a reduced dose of radiation therapy combined with the immunotherapy drug nivolumab against the standard treatment of full-dose radiation plus cisplatin for early-stage HPV-positive oropharyngeal cancer in non-smokers. About 384 participants are enrolled to see…
Matched conditions: CLINICAL STAGE I HPV-MEDIATED (P16-POSITIVE) OROPHARYNGEAL CARCINOMA AJCC V8
Phase 2/3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
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Could less radiation be just as good for HPV throat cancer?
Disease control OngoingThis study looks at whether giving a lower dose of radiation after robotic surgery can help people with HPV-positive throat cancer have fewer side effects, like trouble swallowing, while still controlling the cancer. About 33 adults with this type of cancer will receive the reduc…
Matched conditions: CLINICAL STAGE I HPV-MEDIATED (P16-POSITIVE) OROPHARYNGEAL CARCINOMA AJCC V8
Phase 2 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC