CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY
Clinical trials for CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY explained in plain language.
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Tiny balloon tested to clear Life-Threatening heart blockages
Disease control CompletedThis study tested a very small balloon catheter called Sapphire 3. Doctors used it to gently open long-term, completely blocked heart arteries before placing a stent. Researchers watched 170 patients to see if the device was safe and worked well during the procedure and for 24 ho…
Matched conditions: CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY
Phase: NA • Sponsor: OrbusNeich • Aim: Disease control
Last updated Apr 02, 2026 14:56 UTC
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Placebo vs procedure: can a heart op ease chest pain?
Symptom relief CompletedThis study tested if a specific heart artery procedure (called CTO PCI) could reduce chest pain (angina) in patients who were already taking the best possible medications. 50 patients were randomly assigned to receive either the real procedure or a placebo (fake) procedure, and n…
Matched conditions: CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY
Phase: NA • Sponsor: Mid and South Essex NHS Foundation Trust • Aim: Symptom relief
Last updated Apr 03, 2026 14:42 UTC
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Heart stents Re-Clogging years later: researchers hunt for clues
Knowledge-focused CompletedThis study aimed to understand how often and why stents re-narrow (restenosis) years after a procedure to open a completely blocked heart artery. Researchers followed 294 patients who had received a stent for a chronic total occlusion. They used heart imaging scans taken at least…
Matched conditions: CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY
Phase: NA • Sponsor: Lauri Mansikkaniemi • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC