Chronic myeloid leukemia, chronic phase
Clinical trials for Chronic myeloid leukemia, chronic phase explained in plain language.
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Can a newer drug outperform the standard for chronic myeloid leukemia?
Disease control OngoingThis phase III trial compares two oral drugs, radotinib and imatinib, in adults newly diagnosed with chronic myeloid leukemia in its chronic phase. Researchers want to see if radotinib, taken twice daily, achieves a deeper molecular response at 12 months than imatinib, taken once…
Matched conditions: CHRONIC MYELOID LEUKEMIA, CHRONIC PHASE
Phase 3 • Sponsor: Il-Yang Pharm. Co., Ltd. • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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New CML drug combo strategy aims for deeper remission without lifelong side effects
Disease control OngoingThis study tests a new drug, asciminib, as the first treatment for adults newly diagnosed with chronic myeloid leukemia (CML). If the drug alone does not achieve a deep response within 2 to 3 years, a low dose of another targeted therapy is added. The goal is to see if this appro…
Matched conditions: CHRONIC MYELOID LEUKEMIA, CHRONIC PHASE
Phase 2 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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New combo aims to free CML patients from daily pills
Disease control OngoingThis phase 2 trial tests whether adding ruxolitinib to a standard tyrosine kinase inhibitor (TKI) can help people with chronic myeloid leukemia (CML) stop their medication for longer. Participants had previously tried stopping a TKI but relapsed. The study enrolls 24 adults and m…
Matched conditions: CHRONIC MYELOID LEUKEMIA, CHRONIC PHASE
Phase 2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC