CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)
Clinical trials for CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) explained in plain language.
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New Pill-Infusion combo challenges chemo for CLL patients
Disease control CompletedThis study tested whether a combination of venetoclax (a pill) and obinutuzumab (an infusion) works better than standard chemotherapy for people with untreated chronic lymphocytic leukemia (CLL) who are otherwise healthy. 166 fit adults took part. The goal was to see if the new c…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)
Phase: PHASE3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated May 26, 2026 07:43 UTC
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CAR-T therapy shows promise in Long-Term Follow-Up for blood cancers
Disease control CompletedThis study followed 16 patients with various B-cell cancers (like lymphoma and leukemia) who had already received CLBR001 CAR-T cells. The goal was to check for long-term side effects and see how well the treatment controlled the disease over time. Researchers monitored new or la…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)
Phase: PHASE1 • Sponsor: Calibr, a division of Scripps Research • Aim: Disease control
Last updated May 26, 2026 07:22 UTC
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New combo therapy shows promise for untreated CLL patients
Disease control CompletedThis study tested a treatment plan for people with previously untreated chronic lymphocytic leukemia (CLL). Participants received up to six cycles of a chemotherapy combination (fludarabine, cyclophosphamide, rituximab) plus lenalidomide, followed by lenalidomide alone as mainten…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)
Phase: PHASE2 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated May 18, 2026 12:12 UTC
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New combo therapy shows promise for japanese leukemia patients
Disease control CompletedThis study tested two drug combinations (venetoclax plus obinutuzumab or ibrutinib) in 20 Japanese adults with untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The goal was to see how well the treatments worked and if they were safe. Participants …
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)
Phase: PHASE2 • Sponsor: AbbVie • Aim: Disease control
Last updated May 18, 2026 12:02 UTC
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One donor, two transplants: new hope for patients with blood cancer and kidney failure
Disease control CompletedThis study tested a combined bone marrow and kidney transplant from a partially matched family donor for 10 people with both a serious blood disorder and chronic kidney disease. The goal was to treat both conditions with one donor, potentially reducing the need for lifelong anti-…
Matched conditions: CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 18, 2026 12:01 UTC