CERVICAL CANCERS

This phase II trial is testing whether adding the immunotherapy drug toripalimab to standard chemoradiotherapy can improve outcomes for patients with high-risk locally advanced cervical cancer. About 57 participants will receive the combination, followed by maintenance toripalima…

This study was designed to see if adding immunotherapy to chemotherapy works better than the usual chemoradiotherapy for cervical cancer patients whose cancer had spread to lymph nodes after surgery. The plan was to enroll about 50 patients and track cancer return rates over thre…

This early-stage study tests an experimental pill, ATV-1601, in adults with advanced solid tumors or certain breast cancers that have a specific AKT1 gene change. The main goals are to find a safe dose and check how the drug moves through the body. About 134 participants will tak…

This study looks at whether offering HPV self-sampling kits by mail, pharmacy, or clinic can make cervical cancer screening easier. One thousand women aged 25-65 in Quebec will try different ways to get and return the kit. The goal is to see which method works best and if women f…

This study aims to see if women can collect their own samples for HPV testing at home, making cervical cancer screening easier and more accessible. About 8,000 women aged 30-69 in Indonesia will participate. The goal is to find out how well self-collection works and to improve ea…

This study follows 21 patients who had a very extensive surgery called pelvic exenteration for recurrent gynecologic cancer. The goal is to understand how the surgery affects their quality of life and sexuality using standard questionnaires. The results will help doctors better p…

This study tests whether a nurse-led health coaching program helps women aged 45 to 64 in Hong Kong manage their health better. About 1,728 women will either get the nurse-led program or general health advice. The goal is to see if the program leads to better use of medical resou…

This study looks at whether offering cervical cancer screening in the emergency department helps more people get tested. About 200 women and transgender/non-binary individuals with a cervix, aged 25-65, will be offered a self-sampling kit or clinic referral. Researchers will call…

This study tests whether sharing real-life experiences of people affected by cancer can motivate more adults in rural India to get screened for oral, breast, and cervical cancers. About 1,120 men and women aged 30-59 who have not been screened recently will be randomly assigned t…