Cerebral amyloid angiopathy
Clinical trials for Cerebral amyloid angiopathy explained in plain language.
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New drug aims to stop brain bleeds in rare disease
Disease control OngoingThis study tests an experimental drug called ALN-APP in 200 adults with cerebral amyloid angiopathy (CAA), a condition that causes bleeding in the brain. The drug is given via spinal injection and aims to slow disease progression and reduce new brain bleeds. Participants will be …
Matched conditions: CEREBRAL AMYLOID ANGIOPATHY
Phase 2 • Sponsor: Alnylam Pharmaceuticals • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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Can deep sleep or nerve stimulation flush toxic proteins from the brain?
Disease control By invitation onlyThis Phase 2 trial tests whether a sleep-deepening drug (lower-sodium oxybate) or a nerve-stimulating device (non-invasive vagus nerve stimulation), or both, can help clear amyloid-beta protein from the brain in people with cerebral amyloid angiopathy (CAA). Sixty participants wi…
Matched conditions: CEREBRAL AMYLOID ANGIOPATHY
Phase 2 • Sponsor: Leiden University Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Monthly MRI reveals hidden brain bleeding patterns in elderly
Knowledge-focused OngoingThis study uses monthly MRI scans to closely watch brain changes in 75 people with cerebral amyloid angiopathy (CAA), a condition common in older adults that can cause bleeding and strokes. Researchers aim to understand how small bleeds and silent strokes develop over time. Parti…
Matched conditions: CEREBRAL AMYLOID ANGIOPATHY
Sponsor: Martin Dichgans • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:35 UTC