CANCER CACHEXIA

This early-stage trial tests a new drug called GB18, designed to treat cancer cachexia—a condition where cancer patients lose weight and muscle. The study involves 36 healthy adults to check the drug's safety and how the body processes it. Participants receive a single injection …

This study tests a new drug called JMT203 in people with lung or pancreatic cancer who are losing weight and muscle (cancer cachexia). The goal is to see if the drug is safe and can help patients gain or maintain weight. About 307 adults will take part across two phases, starting…

This study tests an experimental drug called NGM120 in 136 people with colorectal cancer who are experiencing cancer-related weight loss (cachexia). The goal is to see if the drug helps patients gain or maintain weight and is safe to use. Participants will receive either NGM120 o…

This study looks at two different exercise programs—flexi band resistance training and whole-body electrical muscle stimulation—to see which better helps cancer patients maintain muscle strength, reduce inflammation, and improve quality of life during treatment. About 100 adults …

This study tests whether a drug called NPX-5 (psilocybin) combined with talk therapy can reduce severe anxiety in people who have been diagnosed with cancer. About 87 adults aged 18 to 80 will receive one of three doses (25 mg, 10 mg, or 1 mg) during an 8-hour therapy session. Th…

This study looks at whether artificial intelligence can help detect cachexia—a severe loss of weight and muscle—early in people with pancreatic cancer. Researchers will also see if diet and exercise programs are practical and helpful for these patients. About 120 adults with panc…

This study aims to understand why muscle wasting (cachexia) happens in some colorectal cancer patients. Researchers will take small muscle samples and compare them between patients with and without cachexia, as well as healthy volunteers. The goal is to learn more about the muscl…