BPH (benign prostatic hyperplasia)

This trial tests whether a gel called PuraStat, applied during Aquablation surgery for an enlarged prostate, can reduce bleeding and help men recover faster. Half of the 50 participants will receive the gel, and the other half will not. Researchers will measure blood loss in the …

This trial tests whether a new device called Prolieve, which uses microwave heat and balloon dilation, can relieve moderate-to-severe urinary symptoms from an enlarged prostate as effectively as the established UroLift implant procedure. Men aged 50-80 who haven't found relief fr…

This study tests a new robotic-assisted platform, called the Beacon Platform, for a type of prostate surgery known as HoLEP, which treats enlarged prostate symptoms. The trial will enroll 50 men with benign prostatic hyperplasia (BPH) to see if the platform can safely and effecti…

This study tests whether adding raloxifene to the standard drug finasteride works better than finasteride alone for men with an enlarged prostate (BPH). About 242 adults will take either the combo or finasteride plus a placebo for 12 months. The goal is to see if the combo improv…

This study tracks how well the Zenflow Spring System works in everyday medical practice for men with BPH (enlarged prostate). About 300 participants will be followed for a year to see if symptoms improve, how quickly they return to normal activities, and if any side effects occur…

This early study is testing a new, ultra-minimally invasive procedure for men with benign prostatic hyperplasia (BPH) who have significant urinary symptoms. The treatment uses a balloon catheter guided by ultrasound to gently widen the prostate passage. Only 5 men aged 40 to 80 w…

This study compares two laser surgeries—ThuLEP and HoLEP—for treating enlarged prostate symptoms in men. 150 men will be randomly assigned to one of the two procedures and followed for 12 months. The goal is to see which technique provides better symptom relief, faster recovery, …

This study tests a liquid called INTUPRO that is injected into the prostate to shrink tissue and improve urine flow in men with enlarged prostate (BPH). 31 men aged 45+ with moderate to severe symptoms will receive the treatment and be followed for 3 months. The goal is to see if…

This research project tracks men treated with a technology called High-Intensity Focused Ultrasound (HIFU) for prostate cancer or an enlarged prostate. The goal is to see how well this treatment controls disease and affects urinary and sexual function over 10 to 20 years. By coll…