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Bone marrow failure syndromes
Clinical trials for Bone marrow failure syndromes explained in plain language.
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New drug combo aims to make bone marrow transplants safer for kids
Disease control OngoingThis pilot study tests a fludarabine-based drug regimen to prepare children with bone marrow failure syndromes for a bone marrow transplant from a matched sibling donor. The goal is to help the donor cells successfully take root while reducing serious side effects. The study incl…
Matched conditions: BONE MARROW FAILURE SYNDROMES
Early phase 1 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Could methadone ease agonizing mouth pain in kids after transplant?
Symptom relief PausedThis study tests whether adding methadone to usual morphine-based pain medicine reduces severe mouth pain in children aged 6–18 who are getting a stem cell transplant for leukemia, aplastic anemia, or similar conditions. The mouth pain is a common side effect of the chemotherapy …
Matched conditions: BONE MARROW FAILURE SYNDROMES
Phase 3 • Sponsor: University of Texas Southwestern Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC