Blood-brain barrier
Clinical trials for Blood-brain barrier explained in plain language.
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Can antibiotics dripped through the skull bone reach the brain better than IV drugs alone?
Disease control Not yet recruitingResearchers are testing a new way to deliver antibiotics to the brain in people with moderate to severe bacterial meningitis who are not improving on standard intravenous treatment. The approach combines standard IV antibiotics with a continuous infusion of three antibiotics (van…
Matched conditions: BLOOD-BRAIN BARRIER
Sponsor: yilong Wang • Aim: Disease control
Last updated Sep 19, 2026 00:00 UTC
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Skull injection could bypass brain barrier for stroke patients
Disease control Not yet recruitingThis early study tests whether a drug called RK-4 can be safely injected through the skull into the brain of people having a severe stroke. Only 6 participants will receive the injection once a day for 3 days, using a special device. The main goal is to see if the procedure is fe…
Matched conditions: BLOOD-BRAIN BARRIER
Sponsor: yilong Wang • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Brain injection method could revolutionize meningitis treatment
Disease control Not yet recruitingThis study tests a new method of giving antibiotics for moderate-to-severe bacterial meningitis. Instead of only giving antibiotics through a vein, doctors will also inject them into the skull bone to help more medicine reach the brain. The goal is to improve recovery in 86 adult…
Matched conditions: BLOOD-BRAIN BARRIER
Sponsor: yilong Wang • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC