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Blastic plasmacytoid dendritic cell neoplasm
Clinical trials for Blastic plasmacytoid dendritic cell neoplasm explained in plain language.
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Can a targeted drug hit the mark in Hard-to-Treat blood cancers?
Disease control OngoingThis trial tests an experimental drug called IMGN632 in people with certain blood cancers, including acute myeloid leukemia and blastic plasmacytoid dendritic cell neoplasm. The drug is designed to find and attack cancer cells that carry a protein called CD123 on their surface. R…
Matched conditions: BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM
Phase 1/2 • Sponsor: AbbVie • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Could removing certain immune cells prevent a deadly transplant complication?
Disease control OngoingThis study tests whether removing a specific type of immune cell (naive T cells) from donor stem cells can prevent chronic graft-versus-host disease (GVHD) in children and young adults with blood cancers. GVHD occurs when donor cells attack the patient's body after a stem cell tr…
Matched conditions: BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM
Phase 2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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Engineered immune cells take aim at stubborn blood cancers
Disease control OngoingThis early-phase trial tests a new type of immunotherapy for patients with acute myeloid leukemia (AML) or blastic plasmacytoid dendritic cell neoplasm (BPDCN) that has returned or not responded to treatment. Researchers take a patient's own (or a donor's) T-cells, modify them in…
Matched conditions: BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM
Phase 1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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New hope for tough blood cancers: experimental drug MGD024 enters human testing
Disease control OngoingThis early-stage study tests a new drug called MGD024 in people with certain blood cancers (like leukemia and lymphoma) that came back or didn't get better with standard treatments. The main goal is to find the safest dose and watch for side effects. About 130 adults will receive…
Matched conditions: BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM
Phase 1 • Sponsor: MacroGenics • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC