BACTERIAL INFECTIONS

This study tests a new vaccine to protect babies against pneumococcal infections, which can cause pneumonia and meningitis. About 600 healthy infants in Thailand will receive either the new or a standard vaccine at 2, 4, and 12-15 months old. Researchers will check how well the v…

This study tests whether a medicine called XEMBIFY, given every two weeks alongside standard care, can reduce serious bacterial infections in adults with certain blood cancers (chronic lymphocytic leukemia, multiple myeloma, or non-Hodgkin lymphoma) who also have low antibody lev…

This early-phase study is testing a radioactive tracer called [18F]F-TMP to see how it spreads in the body and whether it can help detect bacterial infections using PET/CT scans. About 20 adults with known or suspected bacterial infections will receive the tracer and undergo imag…

This study is collecting blood and saliva samples from 2000 adults who come to the emergency room with a suspected respiratory infection. The goal is to build a biobank and use advanced analysis to better understand these infections, which could lead to improved diagnosis and tre…

This study looks at how well beta-lactam antibiotics work in people with liver cirrhosis and bacterial infections. Researchers will review past and current patient data to build a model that helps doctors choose the right dose for each patient. The goal is to reduce deaths and im…

This early-stage study is testing an experimental antibiotic combination called Cefiderocol/Xeruborbactam in 40 people with different levels of kidney function. Researchers want to see how safe the drug is and how the body processes it after a single dose. The goal is to learn th…

This study looks at how people recover after infective endocarditis, a serious heart infection. Researchers want to see if a 12-week exercise program can improve physical fitness, fatigue, and quality of life. About 50 adults who had the infection will take surveys, do interviews…

This early-stage study is testing a new drug called JKN2501 in 66 healthy adults in China. The goal is to see if the drug is safe and how the body processes it, not to treat any disease. Participants will receive either the drug or a placebo by IV, and researchers will monitor fo…

This study is observing how children with meningitis are treated in hospitals across Brazil and how they recover over time. It will include 600 children under 18 with suspected meningitis. The goal is to learn what works best and where care can be improved, without testing any ne…