AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD
Clinical trials for AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD explained in plain language.
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Can a monthly shot protect kidneys in polycystic disease?
Disease control CompletedThis study tested whether lanreotide, a monthly injection, can slow the loss of kidney function in people with autosomal dominant polycystic kidney disease (ADPKD). The trial included 159 adults with moderate kidney decline and measured changes over three years. Researchers also …
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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Healthy volunteers help test new kidney disease drug
Knowledge-focused CompletedThis study tested a new drug called VX-407 in 32 healthy adults to see if it is safe and how the body handles it. The drug is being developed for a kidney condition called ADPKD. This early research does not offer treatment but gathers important safety information for future stud…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD
Phase: PHASE1 • Sponsor: Vertex Pharmaceuticals Incorporated • Aim: Knowledge-focused
Last updated May 26, 2026 05:12 UTC
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Bergamo gene discovery may explain kidney disease patterns
Knowledge-focused CompletedThis study looked at 10 people with a kidney disease called ADPKD to see if a specific gene change (a deletion in the PKD2 gene) is common in families from the Bergamo area. Researchers interviewed participants about their health and family history to understand how this gene cha…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD
Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Knowledge-focused
Last updated May 26, 2026 05:04 UTC
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Canadian study tracks Real-World impact of kidney drug on Patients' lives
Knowledge-focused CompletedThis study followed 530 adults with autosomal dominant polycystic kidney disease (ADPKD) who were already prescribed tolvaptan (JINARC™) by their doctor. Researchers observed how the drug affected patients' quality of life, pain, and ability to work, as well as how long it took b…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD
Sponsor: Otsuka Canada Pharmaceutical Inc. • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC
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Large study tracks how kidney disease worsens in thousands of patients
Knowledge-focused CompletedThis study followed over 3,400 people with ADPKD, a genetic condition that causes cysts to grow in the kidneys. Researchers measured kidney size and other health changes over time to better understand how the disease progresses. The goal was to identify which patients are at high…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD
Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. • Aim: Knowledge-focused
Last updated May 19, 2026 11:47 UTC
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Drug interaction study: VX-407 and oral contraceptives
Knowledge-focused CompletedThis completed Phase 1 study looked at how a new drug called VX-407 changes the levels of various birth control pills in the body. 74 healthy adults participated to measure drug levels and check safety. The results will help doctors understand if birth control pills work properly…
Matched conditions: AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD
Phase: PHASE1 • Sponsor: Vertex Pharmaceuticals Incorporated • Aim: Knowledge-focused
Last updated May 18, 2026 12:08 UTC