AUD
Clinical trials for AUD explained in plain language.
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Implant shows promise in reducing heavy drinking days
Disease control CompletedThis study tested whether a small, implanted pellet of the medication naltrexone could help adults with moderate to severe alcohol use disorder reduce their drinking. 210 participants received either a low-dose implant, a high-dose implant, or a placebo implant, along with counse…
Matched conditions: AUD
Phase: PHASE2 • Sponsor: Shenzhen Sciencare Medical Industries Co., Ltd. • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Scientists scan brains to see why some drinkers respond differently to medication
Knowledge-focused CompletedThis small, completed study aimed to understand how a medication called nalmefene affects the brain's response to alcohol cues and drinking behavior in heavy drinkers. It also tested whether a specific gene variation (OPRM1) changes how people respond to the medication. Thirteen …
Matched conditions: AUD
Phase: PHASE1 • Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:25 UTC