AORTIC STENOSIS, SEVERE
Clinical trials for AORTIC STENOSIS, SEVERE explained in plain language.
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New heart valve could save thousands from deadly narrowing
Disease control OngoingThis study tests a new balloon-expandable heart valve (SAPIEN X4) in 1,234 people with severe aortic stenosis, a condition where the heart's main valve narrows. The goal is to see if the valve is safe and works well. Participants receive the valve through a tube in their leg, avo…
Matched conditions: AORTIC STENOSIS, SEVERE
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated May 26, 2026 06:47 UTC
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Can TAVI be safely done without a surgery backup? major trial investigates
Knowledge-focused OngoingThis study looks at whether a minimally invasive heart valve replacement (TAVI) is just as safe and effective when done in a center without on-site emergency heart surgery, compared to one with it. About 657 people with severe aortic stenosis who are too high-risk for traditional…
Matched conditions: AORTIC STENOSIS, SEVERE
Phase: NA • Sponsor: Azienda Usl di Bologna • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC